Professor Kramer discusses the controversial topic of public dissection and its impact on the ethics of body donation programs. Drawing on recent events and international ethical frameworks, she will argue that public dissection violates the principles of consent and compromises community trust in these programs. This thought-provoking lecture examines the implications of ethical breaches such as this and other contemporary challenges and propose potential solutions for upholding the dignity of body donors and advancing the field of anatomy.
Dr. Elly Tanaka seeks to understand the cellular mechanisms underlying salamander limb and spinal cord regeneration as a model for how successful regeneration occurs in vertebrates. In addition to being exceptional models for studying regeneration, salamanders are also historically important models for understanding developmental processes. Salamanders therefore act as a starting point to rigorously investigate how mammals such as mice have lost regeneration capabilities during evolution, and they provide a springboard to design novel strategies for regenerating or replacing mammalian tissues. With these goals in mind the Tanaka laboratory has engineered three-dimensional spinal cord tissue and retinal pigment epithelia from embryonic stem cells.
Speaker: Dr. Alino Martínez-Marcos
December 1, 2022
Alzheimer’s and Parkinson’s diseases are the two most prevalent neurodegenerative diseases. The etiology of both diseases are quite different, but both are proteinopathies. The staging of both proteinopathies could be explained based on the prion-like hypothesis. In this talk, Dr. Martínez-Marcos will try to explain how neuropathological stating could be explained based on prion-like hypothesis and connectomics. Classic neuroanatomy will be faced to new -omic approaches.
Speaker: Dr. Akinobu “Aki” Watanabe, New York Institute of Technology College of Osteopathic Medicine
November 8, 2022
The talk features his research on the evolution of distinct cranial architectures in squamate reptiles, origins of highly encephalized brains in birds, and a potential new model system for how unique head structures evolve.
Speaker: Dr. Julie Siegenthaler, Associate Professor, University of Colorado Anshutz Medical Campus
October 6, 2022
The Siegenthaler laboratory studies the interplay between the central nervous system (CNS) and its vital support structures, the meninges and the brain vasculature. The meninges surround the brain and spinal cord providing a protective covering. However, the meninges are also an important source of developmental cues that regulate neuronal migration, cell positioning and neurogenesis. CNS disease and injury are frequently accompanied by breakdown of the meninges and vascular instability, and recently the Siegenthaler laboratory generated a single cell transcriptome atlas of the embryonic mouse meninges. This together with ongoing work has opened the door to a better understanding of the mechanisms underlying vascular and meningeal barrier instability in disease, specifically ischemic stroke, viral encephalitis and bacterial meningitis.
Speakers: Drs. Casey Holliday and Emma Schachner
September 8, 2022
Casey Holliday is an Associate Professor in Integrative Anatomy in the Department of Pathology and Anatomical Sciences at the University of Missouri School of Medicine. Emma R. Schachner is an Associate Professor in the Department of Cell Biology and Anatomy at Louisiana State University Health Sciences Center. Drs. Holliday and Schachner are co-Guest Editors of an upcoming volume of The Anatomical Record on crocodyliform evolution, functional morphology, and paleobiology. The presentation will focus on recent advances in the biology and paleontology of this fascinating lineage of vertebrates. The presenters will discuss how researchers bring crocodylians and their extinct ancestors to life using a variety of approaches including fieldwork, imaging, 3D modeling, developmental biology, physiological monitoring, dissection, and a host of other comparative methods.
Speaker: Dr. Serjoscha Evers, SNSF Ambizione Fellow at the University of Fribourg, Switzerland
May 5, 2022
In this talk, Serjoscha will present aspects from his work on flipper evolution, the ecomorphology of the labyrinth organ, and cranial shape changes associated with diet.
Speaker: Dr. Winfried Neuhuber, Professor, University of Erlangen-Nürnberg, Institute of Anatomy and Cell Biology, Germany
March 3, 2022
Winfried Neuhuber is FAU Senior Professor of Anatomy in the Institute of Anatomy and Cell Biology at Friedrich-Alexander-Universität Erlangen Nürnberg (Germany). His research focus is on the functional anatomy of the autonomic nervous system, in particular innervation of the gastrointestinal tract using neuronal tract tracing and immunohistochemistry. In this talk, he will present some examples of organs which are targeted by both efferent and afferent vagal neurons. In contrast, he will discuss older and more recent claims of vagal innervation which most likely resulted from tracing artifacts or other misconceptions.
Speaker: David Ornitz, MD, Ph.D., Alumni Endowed Professor Washington University School of Medicine in St. Louis
February 3, 2022
David Ornitz is an Alumni Endowed Professor in the Department of Developmental Biology at Washington University School of Medicine. His research uses molecular, genetic, and biochemical approaches to study mesodermal and epithelial patterning, organogenesis, tissue homeostasis, and response to injury.
The Ornitz lab has a particular interest in the function of Fibroblast Growth Factor (FGF) signaling pathways in endochondral bone development, postnatal bone growth, and bone homeostasis. In this talk he will explore the role of an FGF receptor (FGFR) signaling center that is located in a unique perichondrial cell population that functions to regulate the activity of the adjacent growth plate.
He will then discuss studies that explore a novel role for FGFR signaling in the maintenance of osteocyte viability and skeletal homeostasis in adult mice.
Speaker: Elaine A. Ostrander, Ph.D., National Human Genome Research Institute
September 23, 2021
The Ostrander laboratory is interested in understanding the genomic factors which control the enormous amount of morphologic, disease susceptibility and behavioral variation observed in canines across the world. She has studied canine evolution, genome structure and breed formation, producing a clear understanding of how most individual breeds developed. Her most recent focus has been on morphology and evolution, as she seeks to understands the genetic underpinning of morphologic variation of canids, past and present, throughout the world.
Speaker: H. Joe Yost, Ph.D., University of Utah
August 31, 2021
The Yost laboratory seeks to understand the gene regulatory networks and developmental mechanisms that define the identity and position of cells in vertebrate embryos and to utilize this knowledge for the advancement of human medicine. This requires integration of model organism genetics with the discovery of novel disease-causing mutations in human genomes, and the Yost laboratory is recognized as a leader in understanding vertebrate left-right development and its contributions to complex congenital heart defects, which affect approximately thirty-five thousand births per year in the US.
Speaker: Dr. Lori Sussel, University of Colorado
May 27, 2021
The pancreas is a flat elongated pear shaped organ positioned behind the stomach. It is part of the digestive system and endocrine system of vertebrates. The pancreas synthesizes pancreatic juices, which contain enzymes that aid in digestion, and it produces several hormones, including insulin which regulates blood sugar levels. But what controls pancreas development and function? To date, only a handful of regulatory have been thoroughly characterized and many of the molecular pathways that specify islet cell differentiation and function are poorly understood.
Speaker: Gabrielle Kardon, Ph.D., University of Utah
March 25, 2021
How does muscle develop, regenerate, maintain, age, and evolve? These are the questions that drive our research. We focus on muscle stem cells because they are the source of all muscle. We focus on the muscle connective tissue because it provides the niche for muscle stem cells and is critical for muscle form and function. We study how interactions between muscle stem cells and the connective tissue orchestrate development of limb muscles and the diaphragm, regulate muscle regeneration and aging, are the source of birth defects and fibrosis, and shape evolution of the musculoskeletal system.
Speaker: Ralph Marcucio, Ph.D., University of California, San Francisco
February 25, 2021
Sometimes the data that are generated by experiments are very far from what is anticipated. As part of a translational project using cartilage to heal large bone defects, we discovered that chondrocytes transform into osteoblasts. This outcome contradicts more than 100 years of dogma that apoptosis is the terminal fate of chondrocytes, and has led to a discovery of new mechanisms of bone regeneration.